Total Protein and Albumin/Globulin (A/G) Ratio : MedlinePlus Medical Test

What is a total protein and albumin/globulin (A/G) ratio test?

A total protein and albumin/globulin (A/G) ratio test measures the total amount of protein in your blood. There are two major types of protein in the blood:

  • Albumin, which helps keep blood from leaking out of blood vessels. It also helps move hormones, medicines, vitamins, and other important substances throughout the body. Albumin is made in the liver.
  • Globulins, which help fight infection and move nutrients throughout the body. Some globulins are made by the liver. Others are made by the immune system.

The test also compares the amount of albumin in your blood to the amount of globulin. The comparison is called the albumin/globulin (A/G) ratio.

If your total protein levels or A/G ratio results are not normal, it can be a sign of a serious health problem.

Other names: total serum protein, TP albumin/globulin ratio