Low Quality of Life, Falls, and Pre-Frailty are Associated with Depressive Symptoms in Virologically Suppressed PLWHIV in Salvador, Brazil | SpringerLink

  1. Palella FJ, Delaney KM, Moorman AC, et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. N Engl J Med. 1998;338(13):853–60.

  2. Jin Y, Liu Z, Wang X, Liu H, et al. A systematic review of cohort studies of the quality of life in HIV/AIDS patients after antiretroviral therapy. Int J STD AIDS. 2014;25(11):771–7.

  3. Erlandson KM, Plankey MW, Springer G, et al. Fall frequency and associated factors among men and women with or at risk for HIV infection. HIV Med. 2016;17(10):740–8.

  4. Levett TJ, Cresswell FV, Malik MA, Fisher M, Wright J. Systematic review of prevalence and predictors of frailty in individuals with human immunodeficiency virus. J Am Geriatr Soc. 2016;64(5):1006–14.

  5. Nasi M, De Biasi S, Gibellini L, et al. Ageing and inflammation in patients with HIV infection. Clin Exp Immunol. 2017;187(1):44–52.

  6. Zicari S, Sessa L, Cotugno N, et al. Immune activation, inflammation, and non-AIDS co-morbidities in HIV-infected patients under long-term ART. Viruses. 2019;11(3):200.

  7. Ciesla JA, Roberts JE. Meta-analysis of the relationship between HIV infection and risk for depressive disorders. Am J Psychiatry. 2001;158(5):725–30.

  8. Rubin LH, Maki PM. HIV, depression, and cognitive impairment in the era of effective antiretroviral therapy. Curr HIV/AIDS Rep. 2019;16(1):82–95.

  9. Gonzalez JS, Batchelder AW, Psaros C, Safren SA. Depression and HIV/AIDS treatment nonadherence: a review and meta-analysis. J Acquir Immune Defic Syndr. 2011;58(2):181–7.

  10. Tao J, Vermund SH, Qian HZ. association between depression and antiretroviral therapy use among people living with HIV: a meta-analysis. AIDS Behav. 2018;22(5):1542–50.

  11. Zangerle R, Kurz K, Neurauter G, Kitchen M, Sarcletti M, Fuchs D. Increased blood phenylalanine to tyrosine ratio in HIV-1 infection and correction following effective antiretroviral therapy. Brain Behav Immun. 2010;24(3):403–8. https://doi.org/10.1016/j.bbi.2009.11.004.

  12. Zangerle R, Widner B, Quirchmair G, Neurauter G, Sarcletti M, Fuchs D. Effective antiretroviral therapy reduces degradation of tryptophan in patients with HIV-1 infection. Clin Immunol. 2002;104(3):242–7.

  13. Schroecksnadel K, Sarcletti M, Winkler C, et al. Quality of life and immune activation in patients with HIV-infection. Brain Behav Immun. 2008;22(6):881–9.

  14. Whiteford HA, Degenhardt L, Rehm J, et al. Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010. Lancet. 2013;382(9904):1575–86. https://doi.org/10.1016/S0140-6736(13)61611-6.

  15. Betancur MN, Lins L, de Oliveira IR, Brites C. Quality of life, anxiety and depression in patients with HIV/AIDS who present poor adherence to antiretroviral therapy: a cross-sectional study in Salvador, Brazil. Braz J Infect Dis. 2017;21(5):507–14. https://doi.org/10.1016/j.bjid.2017.04.004.

  16. Cunha JA. Manual da versão em português das Escalas Beck. São Paulo: Casa do Psicólogo; 2001.

  17. Gomes-Oliveira MH, Gorenstein C, Neto FL, Andrade LH, Wang YP. Validação da versão Brasileira em Português do Inventário de Depressão de Beck-II numa amostra da comunidade. Rev Bras Psiquiatr. 2012;34(4):389–94.

  18. Lima CT, Freire ACC, Silva APB, Teixeira RM, Farrell M, Prince M. Concurrent and construct validity of the audit in an urban Brazillian sample. Alcohol Alcohol. 2005;40(6):584–9.

  19. Lawford BR, Barnes M, Connor JP, Heslop K, Nyst P, Young RMD. Alcohol use disorders identification test (AUDIT) scores are elevated in antipsychotic-induced hyperprolactinaemia. J Psychopharmacol. 2012;26(2):324–9.

  20. Expert panel on detection, evaluation, and treatment of high blood cholesterol in adults. Executive summary of the third report of the national cholesterol education program (NCEP) Expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III). JAMA. 2001;285(19):2486–97.

  21. Fried LP, Tangen CM, Walston J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001;56(3):146–57.

  22. Lustosa LP, Pereira DS, Dias ngela C, et al. Tradução e adaptação transcultural do Minnesota Leisure Time Activities Questionnaire em idosos. Geriatr Gerontol Aging. 2011;5(2):57–65.

  23. Tassiopoulos K, Abdo M, Wu K, et al. Frailty is strongly associated with increased risk of recurrent falls among older HIV-infected adults. AIDS. 2017;31(16):2287–94.

  24. Mahoney F, Barthel D. Functional evaluation: the barthel index. Md State Med J. 1965;14:61–5.

  25. Minosso J, Amendola F, Alvarenga M, Oliveira M. Validación, en Brasil, del Índice de Barthel en pacientes de edad avanzada tratados en consultas. Acta Paul Enferm. 2010;23(2):218–23.

  26. Lawton MP, Brody EM. Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist. 1969;9(3):179–86.

  27. Lins-kusterer L, Menezes MS, Valdelamar J, et al. Original article validity and reliability of the 36-item short form health survey questionnaire version 2 among people living with HIV in Brazil. Braz J Infect Dis. 2019;23(5):313–21. https://doi.org/10.1016/j.bjid.2019.08.001.

  28. Streiner DL. Starting at the beginning: an introduction to coefficient alpha and internal consistency. J Pers Assess. 2003;80(1):99–103.

  29. Jum Nunnally IB. Book review: psychometric theory (3rd ed.). J Psychoeduc Assess. 1994;17(3):275–80.

  30. Rodkjaer L, Laursen T, Balle N, Sodemann M. Depression in patients with HIV is under-diagnosed: a cross-sectional study in Denmark. HIV Med. 2010;11(1):46–53.

  31. Reis RK, Haas VJ, dos Santos CB, Teles SA, Galṽ MT, Gir E. Sintomas de depressão e qualidade de vida de pessoas vivendo com HIV/AIDS. Rev Lat Am Enfermagem. 2011;19(4):874–81.

  32. Judd F, Komiti A, Chua P, et al. Nature of depression in patients with HIV/AIDS. Aust N Z J Psychiatry. 2005;39(9):826–32.

  33. Wulunggono W, Yunihastuti E, Shatri H, Wahyudi ER, Ophinni Y. Frailty among HIV-1 infected adults under antiretroviral therapy in Indonesia. Curr HIV Res. 2019;17(3):204–13.

  34. Kalichman SC, Sikkema KJ, Somlai A. Assessing persons with human immunodeficiency virus (HIV) infection using the beck depression inventory: disease processes and other potential confounds. J Pers Assess. 1995;64(1):86–100.

  35. Pinto M, Silveira T, Guttier MC, et al. Depressive symptoms in HIV-infected patients treated with highly active antiretroviral therapy. Rev Bras Psiquiatr. 2012;34(2):162–7.

  36. Gascón MRP, Vidal JE, Mazzaro YM, et al. Neuropsychological assessment of 412 HIV-infected individuals in São Paulo, Brazil. AIDS Patient Care STDS. 2018;32(1):1–8.

  37. Rezaei S, Ahmadi S, Rahmati J, et al. Global prevalence of depression in HIV/AIDS: A systematic review and meta-analysis. BMJ Support Palliat Care. 2019;9(4):404–12.

  38. Gibbie T, Mijch A, Ellen S, et al. Depression and neurocognitive performance in individuals with HIV/AIDS: 2-year follow-up. HIV Med. 2006;7(2):112–21.

  39. Judd FK, Cockram AM, Komiti A, Mijch AM, Hoy J, Bell R. Depressive symptoms reduced in individuals with HIV/AIDS treated with highly active antiretroviral therapy: a longitudinal study. Aust N Z J Psychiatry. 2000;34(6):1015–21.

  40. Paterson DL, Swindells S, Mohr J, et al. Adherence to protease inhibitor therapy and outcomes in patients with HIV infection. Ann Intern Med. 2000;133(1):21–30.

  41. Bromet E, Andrade LH, Hwang I, et al. Cross-national epidemiology of DSM-IV major depressive episode. BMC Med. 2011;26:9.

  42. Weissman MM, Bland RC, Canino GJ, et al. Cross-national epidemiology of major depression and bipolar disorder. JAMA. 1996;276(4):293–9.

  43. Instituto Brasileiro de Geografia e Estatística [internet]. Panorama Cidades: Salvador – IBGE. [cited 2021 Apr 29]. Available from: https://cidades.ibge.gov.br/brasil/ba/salvador/panorama

  44. Ciesla JA, John MA, Roberts E. Meta-analysis of the relationship between HIV infection and risk for depressive disorders. Am J Psychiatry. 2001;158:725.

  45. De Mello VA, Malbergier A. Depression in women infected with HIV Depressão em mulheres infectadas pelo HIV. Braz J Psychiatry. 2006;28(1):10–7.

  46. Ding Y, Lin H, Liu X, et al. Higher prevalence of frailty among a sample of HIV-infected middle-aged and older Chinese adults is associated with neurocognitive impairment and depressive symptoms. J Infect Dis. 2017;215:687–92.

  47. Kooij KW, Wit FWNM, Schouten J, et al. HIV infection is independently associated with frailty in middle-aged HIV type 1-infected individuals compared with similar but uninfected controls. AIDS. 2016;30(2):241–50.

  48. Önen NF, Patel P, Baker J, et al. Frailty and pre-frailty in a contemporary cohort of HIV-infected adults. J Frailty Aging. 2014;3(3):158–65.

  49. Önen NF, Agbebi A, Shacham E, Stamm KE, Önen AR, Overton ET. Frailty among HIV-infected persons in an urban outpatient care setting. J Infect. 2009;59(5):346–52.

  50. Paul RH, Cooley SA, Garcia-Egan PM, Ances BM. Cognitive performance and frailty in older HIV-positive adults. J Acquir Immune Defic Syndr. 2018;79(3):375–80

  51. Rees HC, Meister E, Mohler MJ, Klotz SA. HIV-related frailty is not characterized by Sarcopenia. J Int Assoc Provid AIDS Care. 2016;15(2):131–4.

  52. American Psychiatric Association. Diagnostic and statistical manual of mental disorders, vol. 17. Washington: American Psychiatric Association; 2013. p. 461–2. https://doi.org/10.1176/appi.books.9780890425596.

  53. Vaughan L, Corbin AL, Goveas JS. Depression and frailty in later life: a systematic review. Clin Interv Aging. 2015;10:1947–58.

  54. Schoene D, Heller C, Aung YN, Sieber CC, Kemmler W, Freiberger E. A systematic review on the influence of fear of falling on quality of life in older people: is there a role for falls? Clin Interv Aging. 2019;14:701–19.

  55. Erlandson KM, Allshouse AA, Jankowski CM, et al. Risk factors for falls in HIV-infected persons. J Acquir Immune Defic Syndr. 2012;61(4):484–9

  56. Erlandson KM, Zhang L, Ng DK, Althoff KN, Palella FJ, Kingsley LA, et al. Risk factors for falls, falls with injury, and falls with fracture among older men with or at risk of HIV infection. J Acquir Immune Defic Syndr. 2019;81(4):e117–e126.

  57. Valdelamar-Jiménez J, Lins-Kusterer L, de Jesus STG, Netto EM, Brites C. Comparison of three health-related quality of life instruments to evaluate symptoms of depression in HIV patients in Brazil. J Clin Psychol Med Settings. 2019. https://doi.org/10.1007/s10880-019-09657-9.

  58. Zeballos D, Lins L, Brites C. Frailty and its association with health related quality of life in older HIV patients, in Salvador, Brazil. AIDS Res Hum Retroviruses. 2019;35(11–12):1074–81.

  59. Pompili M, Pennica A, Serafini G, et al. Depression and affective temperaments are associated with poor health-related quality of life in patients with HIV infection. J Psychiatr Pract. 2013;19(2):109–17.

  60. Tate D, Paul RH, Flanigan TP, et al. The impact of apathy and depression on quality of life. AIDS Patient Care STDS. 2003;17(3):115–20.

  61. Scott W, Arkuter C, Kioskli K, et al. Psychosocial factors associated with persistent pain in people with HIV. Pain. 2018;159(12):2461–76.

  62. Pereira AC, Bradbury F, Rossetti ES, Hortense P. Assessment of pain and associated factors in people living with HIV/AIDS. Rev Lat Am Enfermagem. 2019;27:e3155.

  63. Horwitz AV, Wakefield JC. The loss of sadness: how psychiatry transformed normal sorrow into depressive disorder. First. Oxford: Oxford University Press; 2012. p. 304.