Top 12 quality of life after low anterior resection in 2023

Author: pubmed.ncbi.nlm.nih.gov

Date Submitted: 08/01/2019 09:44 AM

Average star voting: 3 ⭐ ( 47638 reviews)

Summary: Patients who underwent low anterior resection with ileostomy had significant reductions in physical and role functioning, which apparently improved after ileostomy closure. Similar declines in these quality of life variables were not found in patients who underwent high anterior resection. A tempora …

Match with the search results: Conclusion: Patients who underwent low anterior resection with ileostomy had significant reductions in physical and role functioning, which apparently improved ……. read more

Author: www.ncbi.nlm.nih.gov

Date Submitted: 04/15/2021 12:48 AM

Average star voting: 3 ⭐ ( 19546 reviews)

Summary:

Match with the search results: After a low anterior resection, elderly patients who have had rectal cancer have a decreased QoL due to fecal incontinence. Elderly female ……. read more

Author: journals.lww.com

Date Submitted: 06/23/2021 04:26 AM

Average star voting: 3 ⭐ ( 18085 reviews)

Summary:

Match with the search results: According to our definitions, 29 patients (10%) deteriorated, 40 improved (14%), and 213 were stable in their LARS symptoms (stable “good” 104 (37%); stable “ ……. read more

Author: www.frontiersin.org

Date Submitted: 01/15/2019 09:55 PM

Average star voting: 5 ⭐ ( 38584 reviews)

Summary: Objectives: Lower rectal resection is associated with a high rate of postoperative complications and, therefore, adversely impacts the postoperative health-related quality of life (QoL). Though sporadically practiced in different centers, there is no standard perioperative protocol for the management of patients with rectal growths. The aim of this analysis is to evaluate the patient-reported outcomes after low rectal resections followed by an end-to-end-reconstruction and temporary covering ileostomy using a multidisciplinary fail-safe-concept. Methods: Between 2015 and 2020, we evaluated patient reported outcomes after open and laparoscopic rectal resections with end-to-end reconstruction with a primary straight anastomosis using a standardized perioperative pathway All patients with stoma were excluded from the study. The data for the QoL of patients was collected using the established Low Anterior Resection Syndrome (LARS) -score and the EORTC-C30 and CR-29 questionnaires at a single postoperative timepoint. Results: We recruited 78 stoma-free patients for this analysis. Of 78 patients included in the study, 87.2 % were operated laparoscopically and the mean global health status was 67.95 points, while a major LARS was detected in 48 (61.5 %) patients. No anastomotic leakage (AL) occurred within the study cohort. There was no significant change in the LARS-score or the global health status depending on the follow-up-period. Conclusion: This study shows that good QoL and functional outcomes with no AL are achievable following end-to-end straight anastomosis using a standardized perioperative surgical fail-safe protocol procedure.

Match with the search results: The most reported adverse mid-term-consequence of low anterior resection (LAR) is a deranged bowel function, often referred as “low anterior ……. read more

Author: www.frontiersin.org

Date Submitted: 11/25/2020 01:02 AM

Average star voting: 4 ⭐ ( 84151 reviews)

Summary: Background: Despite improvements in surgical techniques, functional outcomes and quality of life after therapy for rectal cancer remain suboptimal. Objective: We sought to prospectively evaluate the effect of bowel, bladder, and sexual functional outcomes on health-related quality of life (QOL) in patients with restorative versus non-restorative resections after rectal cancer surgery. Methods: A cohort of 211 patients with clinical stage I-III rectal cancer who underwent open surgery between 2006 and 2009 at Memorial Sloan Kettering were included. Subjects were asked to complete surveys preoperatively and at 6, 12, and 24 months after surgery. Validated instruments were used to measure QOL, bowel, bladder, and sexual function. Univariable and multivariable regression analyses evaluated predictors of 24- month QOL. In addition, longitudinal trends over the study period were evaluated using repeated measures models. Results: In total, 180 patients (85%) completed at least 1 survey, and response rates at each time point were high (>70%). QOL was most impaired at 6 and 12 months and returned to baseline levels at 24 months. Among patients who underwent sphincter-preserving surgery (SPS; n=153 [85%]), overall bowel function at 24 months was significantly impaired and never returned to baseline. There were no differences in QOL at 24 months between patients who underwent SPS and those who did not (p=.29). Bowel function was correlated with QOL at 24 months (Pearson correlation, .41; p<.001). Conclusion: QOL among patients who have undergone SPS for rectal cancer is good despite poor function. Patients with ostomies are able to adjust to the functional changes and, overall, have good global QOL. Patients with low anastomoses had lower global QOL at 24 months than patients with permanent stomas. Our findings can help patients set expectations about function and quality of life after surgery for rectal cancer with and without a permanent stoma.

Match with the search results: QOL was most impaired at 6 and 12 months and returned to baseline levels at 24 months. Among patients who underwent sphincter-preserving surgery ……. read more

Author: jgo.amegroups.com

Date Submitted: 12/27/2019 03:14 AM

Average star voting: 3 ⭐ ( 27332 reviews)

Summary: Is my life going to change?—a review of quality of life after rectal resection

Match with the search results: On the other hand, there are studies found that patients after LAR scored higher in emotional and cognitive functioning (18,73), but other studies reported that ……. read more

Author: www.loveyourbuns.org

Date Submitted: 11/11/2020 12:07 PM

Average star voting: 4 ⭐ ( 32545 reviews)

Summary:

Match with the search results: If your treatment requires a Low Anterior Resection, you may be at risk for LARS. What symptoms should you expect after surgery? · Extremely increased frequency ……. read more

Author: www.thelancet.com

Date Submitted: 04/24/2020 06:25 AM

Average star voting: 4 ⭐ ( 61201 reviews)

Summary:

Match with the search results: The 5-year overall survival was worse with abdominoperineal resection in unadjusted (92•2% vs 80•9%; difference 11•3%, hazard ratio 2•38; 95% CI ……. read more

Author: academic.oup.com

Date Submitted: 07/17/2020 03:48 AM

Average star voting: 4 ⭐ ( 49659 reviews)

Summary: AbstractBackground. The prevalence of major low anterior resection syndrome (LARS) after rectal cancer surgery varies from 17·8 to 56·0 per cent, but data from

Match with the search results: After anterior resection for rectal cancer, the majority of patients suffer from major LARS with a negative impact on QoL. Resumen. Antecedentes….. read more

Author: www.karger.com

Date Submitted: 02/28/2021 01:37 AM

Average star voting: 5 ⭐ ( 19868 reviews)

Summary: Introduction: Compared to abdominoperineal resection (APR), sphincter preservation using low anterior resection (AR) for rectal cancer (RC) implies the risk of impaired functional outcom

Match with the search results: Results: Questionnaires from 57 APR, 165 AR, and 25 COT patients alive were evaluated after a median time of 4 years after surgery. Global ……. read more

Author: www.cancer.org

Date Submitted: 08/17/2020 12:50 AM

Average star voting: 5 ⭐ ( 52926 reviews)

Summary: Surgery is often the main treatment for rectal cancer. Learn about the different types of surgeries for rectal cancer and their possible risks & side effects.

Match with the search results: Conclusion: Patients who underwent low anterior resection with ileostomy had significant reductions in physical and role functioning, which apparently improved ……. read more

Author: trialsjournal.biomedcentral.com

Date Submitted: 02/02/2019 04:03 AM

Average star voting: 4 ⭐ ( 71387 reviews)

Summary: After low anterior resection (LAR), up to 90% of patients develop anorectal dysfunction. Especially fecal incontinence has a major impact on the physical, psychological, social, and emotional functioning of the patient but also on the Dutch National Healthcare budget with more than €2000 spent per patient per year. No standardized treatment is available to help these patients. Common treatment nowadays is focused on symptom relief, consisting of lifestyle advices and pharmacotherapy with bulking agents or antidiarrheal medication. Another possibility is pelvic floor rehabilitation (PFR), which is one of the most important treatments for fecal incontinence in general, with success rates of 50–80%. No strong evidence is available for the use of PFR after LAR. This study aims to prove a beneficial effect of PFR on fecal incontinence, quality of life, and costs in rectal cancer patients after sphincter-saving surgery compared to standard treatment. The FORCE trial is a multicenter, two-armed, randomized clinical trial. All patients that underwent LAR are recruited from the participating hospitals and randomized for either standard treatment or a standardized PFR program. A total of 128 patients should be randomized. Optimal blinding is not possible. Stratification will be done in variable blocks (gender and additional radiotherapy). The primary endpoint is the Wexner incontinence score; secondary endpoints are health-related and fecal-incontinence-related QoL and cost-effectiveness. Baseline measurements take place before randomization. The primary endpoint is measured 3 months after the start of the intervention, with a 1-year follow-up for sustainability research purposes. The results of this study may substantially improve postoperative care for patients with fecal incontinence or anorectal dysfunction after LAR. This section provides insight in the decisions that were made in the organization of this trial. Netherlands Trial Registration, NTR5469, registered on 03-09-2015. Protocol FORCE trial V18, 19-09-2019. Sponsor Radboud University Medical Center, Nijmegen.

Match with the search results: After a low anterior resection, elderly patients who have had rectal cancer have a decreased QoL due to fecal incontinence. Elderly female ……. read more