Top 12 serum 18f in 2023

Author: pubmed.ncbi.nlm.nih.gov

Date Submitted: 10/31/2022 02:47 AM

Average star voting: 4 ⭐ ( 97392 reviews)

Summary:

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Author: pubmed.ncbi.nlm.nih.gov

Date Submitted: 04/16/2020 06:46 PM

Average star voting: 5 ⭐ ( 83521 reviews)

Summary: Background Classical Hodgkin lymphoma (cHL) is a heterogeneous disease characterized by a limited number of Hodgkin Reed-Sternberg (HRS) cells in a complex tumo

Match with the search results: The diagnostic value of 18F-FDG PET/CT in association with serum tumor marker assays in breast cancer recurrence and metastasis….. read more

Author: journals.lww.com

Date Submitted: 03/15/2019 02:23 PM

Average star voting: 3 ⭐ ( 10757 reviews)

Summary: Objective To evaluate the value of using 18F-FDG PET/CT imaging in combination with serum lactate dehydrogenase (LDH) for predicting the prognosis of newly diagnosed small cell lung cancer (SCLC). Methods We reviewed 118 patients with pathologically proven SCLC who underwent 18F-FDG PET/CT imaging evaluation in our hospital. Among these patients, 54 patients were limited disease (LD), and 64 patients were extensive disease (ED). The maximum standardized uptake value (SUVmax) of primary tumor was measured. A Cox proportional hazards model was used to evaluate age, sex, performance status, lactate dehydrogenase (LDH), tumor stage and SUVmax on the prediction of overall survival (OS) and median survival time (MST) of patients. Subgroup analysis was performed based on the SUVmax in combination with LDH. Results According to the ROC curve, the optimal cut-off value of SUVmax was 10.95. The AUC was 0.535 (95% CI: 0.407 ~ 0.663). The patients were divided into four groups according to the SUVmax (cut-off 10.95) and LDH (cut-off 245 U/L). In LD. There was no significant difference in MST among the different groups (p =0.057). In patients with ED, there was no significant difference in MST among the different groups (p =0.742). Among all patients, 27 had low SUVmax and normal LDH, and their MST was 36 months (95% CI, 12.98-59.02); 91 patients had high SUVmax and/or high LDH, and their MST was 20 months (95% CI, 15.47~24.53). The difference between these two groups was significant (p =0.045). In patients with LD, 16 patients had low SUVmax and normal LDH, and their MST was 72 months (95% CI, 26.00 ~118.0); 38 patients had high SUVmax and/or high LDH, and their MST was 27 months (95% CI, 20.80~33.21). The difference between these two groups was significant (p=0.012). Conclusion 18F-FDG PET/CT in combination with serum LDH were prognostic factors of overall survival of SCLC patients. The prognosis of patients with LD SCLC who had low SUVmax of the primary tumor and normal LDH was better than that of patients with high SUVmax and/or high LDH.

Match with the search results: Our study demonstrated that dual-phase 18F-FDG SPECT in association with PCT could be a valuable tool for diagnosis in tumor patients with FUO….. read more

Author: pubs.acs.org

Date Submitted: 01/28/2019 08:34 AM

Average star voting: 3 ⭐ ( 67473 reviews)

Summary: We aimed to evaluate the correlation between 2-deoxy-2-[18F]fluoro-D-glucose (FDG) uptake and disease activity assessed by serum inflammatory biomarker levels in patients with spondyloarthritis (SpA). A total of 36 SpA patients (24 untreated and 12 treated) were examined using FDG positron emission tomography (PET)/computed tomography and classified into axial SpA (axSpA) and peripheral SpA (pSpA). FDG uptake was evaluated in 23 regions of the body and scored as follows: 0 = less than liver uptake; 1 = more than or equal to liver uptake; and 2 = more than or equal to twice liver uptake. A score of 1 or 2 was considered positive. The number of positive regions and the total score were counted in each patient. The maximum standardized uptake value (SUVmax) was calculated for each region, and maximum SUVmax (MaxSUVmax) was used as a representative value. Correlation of PET findings with serum inflammatory biomarker levels, including C-reactive protein (CRP), erythrocyte sedimentation rate, and matrix metalloproteinase 3 (MMP-3), was analyzed. All but two patients had at least one positive lesion. PET indices correlated significantly with most of the serum inflammatory biomarker levels in untreated SpA, but not in treated SpA. Further, MaxSUVmax, number of positive regions, and total score correlated significantly with CRP (all P values < 0.001), and the number of positive regions (P = 0.012) and total score (P = 0.007) correlated significantly with MMP-3 in untreated pSpA. PET indices did not correlate with any serum inflammatory biomarker level in untreated axSpA. FDG uptake in untreated pSpA correlated significantly with serum inflammatory biomarker levels.

Match with the search results: Objective Hyperglycemia has been shown to influence fluorine-18 fluorodeoxyglucose (18F-FDG) upta….. read more

Author: ashpublications.org

Date Submitted: 05/28/2021 01:26 AM

Average star voting: 4 ⭐ ( 90200 reviews)

Summary:

Match with the search results: In this paper, we evaluated the efficacy of this method using human serum albumin (HSA) as a test protein. The resulting product, 18F-HSA, might ……. read more

Author: www.frontiersin.org

Date Submitted: 04/03/2019 05:05 AM

Average star voting: 4 ⭐ ( 67711 reviews)

Summary:

Match with the search results: Tumor Microenvironment Composition Correlates with Quantitative 18F-FDG PET-CT Features and Serum TARC in Patients with Relapsed or Refractory ……. read more

Author: academic.oup.com

Date Submitted: 03/09/2022 12:36 PM

Average star voting: 3 ⭐ ( 20495 reviews)

Summary: 18F-FDG PET/CT is used to diagnose cardiac sarcoidosis and endocarditis. It requires myocardial glucose utilization (MGU) suppression to avoid false positi

Match with the search results: Objective: To investigate the value of using 18F-FDG PET/CT in combination with serum lactate dehydrogenase (LDH) for prognostic evaluation ……. read more

Author: ejnmmires.springeropen.com

Date Submitted: 02/10/2019 09:03 AM

Average star voting: 5 ⭐ ( 37715 reviews)

Summary: Purpose: To explore the correlations between neuron‑specific enolase (NSE) and the metabolic parameters such as the maximum uptake (SUVmax), metabolic tumor volume (MTV) and total lesion glycolysis (TLG), determined by fluorine‑18 fluorodeoxyglucose (

Match with the search results: Quantitative PET/CT uptake and a blood inflammatory panel did not have utility in differentiating the two conditions in our population….. read more

Author: clinicaltrials.gov

Date Submitted: 12/16/2021 02:20 PM

Average star voting: 3 ⭐ ( 51577 reviews)

Summary: Ovarian cancer (OC) is the most fatal gynecological malignancy, and identifying reliable prognostic indicators can help guide therapeutic treatment. Various tumor marker-guided treatment regimens can considerably improve patient prognosis with a better understanding of the molecular underpinnings of ovarian cancer recurrence and metastasis. Fluorine-18-fluorodeoxyglucose Positron emission tomography/computed tomography (18F-FDG PET/CT) is a molecular imaging tool that provides anatomical and functional information about the tumor, and its volume-based metabolic parameters allow for quantifiable observation of ovarian cancer recurrence, prognosis, and therapeutic efficacy. The combined utilization of serological and radiologic markers has been found to provide increased clinical benefit. This article reviewed the predictive value of serum tumor markers and 18F-FDG PET/CT volumetric metabolic parameters for the prognosis of patients with ovarian cancer.

Match with the search results: Background. We aimed to evaluate the correlation between 2-deoxy-2-[18F]fluoro-D-glucose (FDG) uptake and disease activity assessed by serum ……. read more

Author: jnm.snmjournals.org

Date Submitted: 03/31/2021 12:40 AM

Average star voting: 4 ⭐ ( 58985 reviews)

Summary:

Match with the search results: Serum prostate specific antigen (PSA) testing has been relied upon heavily as a marker of disease and is commonly used in the community to guide therapy. PyL, ……. read more

Author: snucm.elsevierpure.com

Date Submitted: 09/22/2022 07:21 PM

Average star voting: 3 ⭐ ( 76067 reviews)

Summary: Purpose To perform a systematic review of the effect of blood glucose levels on 2-Deoxy-2-[18F]fluoro-D-glucose (18F-FDG) uptake in normal organs. Methods We searched the MEDLINE, EMBASE and Cochrane databases through 22 April 2017 to identify all relevant studies using the keywords “PET/CT” (positron emission tomography/computed tomography), “standardized uptake value” (SUV), “glycemia,” and “normal.” Analysis followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses recommendations. Maximum and mean SUVs and glycemia were the main parameters analyzed. To objectively measure the magnitude of the association between glycemia and 18F-FDG uptake in different organs, we calculated the effect size (ES) and the coefficient of determination (R2) whenever possible. Results The literature search yielded 225 results, and 14 articles met the inclusion criteria; studies included a total of 2714 (range, 51–557) participants. The brain SUV was related significantly and inversely to glycemia (ES = 1.26; R2 0.16–0.58). Although the liver and mediastinal blood pool were significantly affected by glycemia, the magnitudes of these associations were small (ES = 0.24–0.59, R2 = 0.01–0.08) and negligible (R2 = 0.02), respectively. Lung, bone marrow, tumor, spleen, fat, bowel, and stomach 18F-FDG uptakes were not influenced by glycemia. Individual factors other than glycemia can also affect 18F-FDG uptake in different organs, and body mass index appears to be the most important of these factors. Conclusion The impact of glycemia on SUVs in most organs is either negligible or too small to be clinically significant. The brain SUV was the only value largely affected by glycemia.

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Author: www.mayoclinicproceedings.org

Date Submitted: 08/03/2020 09:52 PM

Average star voting: 3 ⭐ ( 33692 reviews)

Summary: OBJECTIVE: To explore the clinical application value of 18F-fluorodeoxyglucose (18F-FDG) PET/CT imaging combined with detection of serum tumor molecular

Match with the search results: The diagnostic value of 18F-FDG PET/CT in association with serum tumor marker assays in breast cancer recurrence and metastasis….. read more